Propose a mechanism for the acid-catalyzed reaction of cyclohexan... | Study Prep in Pearson
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Propose a mechanism for the acid-catalyzed reaction of cyclohexan... | Study Prep in Pearson
Propose a mechanism for the acid-catalyzed reaction of cyclohexan... | Study Prep in Pearson
Jul 23, 2022
Cyclohexanone Synthesis
Synthesis of alcohols using Grignard reagents I
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23-64 The Stork enamine reaction and the intramolecular aldol reaction canbe carried out in sequence to allow the synthesis of cyclohexenones.For example, reaction of the pyrrolidine enamine of cyclohexanonewith 3-buten-2-one, followed by enamine hydrolysis and base treat-ment, yields the product indicated. Write each step, and show themechanism of each.
23-64 The Stork enamine reaction and the intramolecular aldol reaction canbe carried out in sequence to allow the synthesis of cyclohexenones.For example, reaction of the pyrrolidine enamine of cyclohexanonewith 3-buten-2-one, followed by enamine hydrolysis and base treat-ment, yields the product indicated. Write each step, and show themechanism of each.
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