The Fischer–Speier esterification enables the acid-catalyzed formation of esters from carboxylic acids and alcohols under equilibrium conditions. Developed by Emil Fischer and Arthur Speier in the late 19th century, the reaction proceeds via protonation of the carbonyl group, nucleophilic attack by the alcohol, and subsequent elimination of water to form the ester. Learn. Review. Repeat.
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Dr. Xanthine on Instagram: "other than SN1, what's your favorite reaction in first semester ochem? source footage from: Determining SN1, SN2, E1, and E2 Reactions: Crash Course Organic Chemistry, University of Surrey SN1 Reactions, EduCat.ninja SN1 - Unimolecular Nucleophilic Substitution animation. Fu GC. Transition-Metal Catalysis of Nucleophilic Substitution Reactions: A Radical Alternative to SN1 and SN2 Processes. ACS Cent Sci. 2017 Jul 26;3(7):692-700. "Nucleophilic substitution of an alky
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