med's go on Instagram: "Valproic acid is contraindicated in pregnancy because it is a potent teratogen associated with neural tube defects, such as spina bifida, due to impaired folate metabolism. While lithium carries a risk of Ebstein anomaly and lamotrigine is relatively safer, valproate has the highest risk for major congenital malformations. Atypical antipsychotics like quetiapine and lurasidone are generally safer options during pregnancy. Therefore, valproic acid is the drug that must be

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