The peptide known as SNAP-8 (acetyl octapeptide-3) has intrigued the scientific community with a molecular design that suggests a potential to modulate neuromuscular communication pathways via SNARE ...
The peptide commonly referred to as SNAP-8 (acetyl octapeptide-3) is a synthetic fragment derivative of SNAP-25, engineered to modulate the SNARE complex and potentially support neurotransmitter ...
The chaperone Hsc70 (green) helps keep SNAP-25 in the proper shape so that it can help form the SNARE complex, enabling neurotransmission. AMHERST, Mass. – A team of researchers from the University of ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
For this article, Eugene Russo interviewed Axel T. Brunger, a Howard Hughes Medical Institute investigator and professor of molecular and cellular physiology at Stanford University. Data from the Web ...
A team of researchers from the University of Massachusetts Amherst is the first to show how proteins called "chaperones" are vital in ensuring that neurons can transmit signals to one another. When ...
A team of researchers shows how proteins called 'chaperones' are vital in ensuring that neurons can transmit signals to one another. When this neurotransmission breaks down, devastating diseases such ...
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