A team from Würzburg has fundamentally changed our understanding of platelet biology. The researchers demonstrate that the ...

Platelets are small, anucleate blood cells that play an essential role in hemostasis. Their primary task is to recognize vascular injury, become activated, and aggregate via their surface receptor ...

Scientists at the Walter and Eliza Hall Institute have identified a way that chemotherapy causes platelet numbers to drop, answering in the process a decade-old question about the formation of ...

They discovered that the progenitor cells of MKs are fully consumed and constantly replaced during platelet formation (thrombopoiesis). This decisive process is regulated by the innate immune system ...

In a recent study under review in the Journal of Hematology & Oncology journal and currently available on the Research Square* preprint server, researchers investigated the presence of severe acute ...

Megakaryocytes, which are derived from hematopoietic stem cell precursors in bone marrow, form and release platelets; these circulate in the blood for 8 to 10 days before they are removed by hepatic ...

Researchers from University of Michigan presented preclinical data for the novel oxylipin analogue CS-585 being developed as an antithrombotic agent. CS-585 was synthesized as an orally available ...

An expert discusses how rilzabrutinib, a recently FDA-approved Bruton tyrosine kinase (BTK) inhibitor, targets the autoimmune pathophysiology of immune thrombocytopenia (ITP) by modulating B cells, ...

Neonatal alloimmune thrombocytopenia (NAIT) is a disorder that affects pregnant people and their fetuses. It occurs when the birthing parent’s immune system produces antibodies that attack and destroy ...

Macrothrombocytopenia (MTC) is a blood disorder in which blood cells called platelets are abnormally large. People with MTC also have thrombocytopenia, a low platelet count. MTC impairs blood clotting ...