The PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity, while PIM-1 and PIM-3 are positive regulators, report Medical University of South Carolina (MUSC) ...
The Pim kinase family of serine/threonine kinases is composed of three isoforms, Pim-1, Pim-2 and Pim-3, which have an important role in tumor progression. Pim kinases suppress apoptosis and regulate ...
(Philadelphia, PA) – Researchers at the Abramson Family Cancer Research Institute at the University of Pennsylvania have determined that a key enzyme, Pim-2, is responsible for the survival of cancer ...
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