Recent trends in directed enzyme evolution focus on combining high-throughput screening methods with advanced biophysical tools and data-driven computational approaches. However, these methods pose ...

Researchers have shown how laboratory evolution can give rise to highly efficient enzymes for new-to-nature reactions, opening the door for novel and more environmentally friendly ways to make drugs ...

Directed evolution—a process in which a protein library is subjected to repeated rounds of mutation and selection to achieve desired properties—can improve the catalytic performance of computationally ...

Enzymes catalyze chemical reactions in organisms—without which life would not be possible. Leveraging AlphaFold2 artificial intelligence, researchers at Charité—Universitätsmedizin Berlin have now ...

This release is available in German. Engineers are unlikely to tinker with the cooling system if they want to increase the size of an engine. Yet chemists at the Max Planck Institute for Coal Research ...

Addressing the global plastic waste crisis, particularly hard-to-recycle blended PET fibers, demands environmentally friendlier recycling methods. Researchers engineered a novel PET hydrolase PET2-21M ...

Landfills are overflowing with plastic trash. Serial inventor Jonathan Rothberg’s Protein Evolution found a solution: using AI to create enzymes that can recycle old polyester textiles into a material ...

Directed evolution is a laboratory method that speeds up protein mutations to help create novel cancer and neurodegenerative disorder therapies. In a new study, scientists detail a method called ...