Communication between oocytes and granulosa cells is essential for oocyte formation, dormancy, reawakening, and maturation. Researchers have demonstrated that a protein complex called the exocyst ...

DLGAP5 is proposed as a causal gene related to oocyte meiosis disorder for the first time. It expanded the current spectrum of pathogenic genes responsible for the phenotype of oocyte maturation and ...

The accumulation of misfolded or damaged proteins in long-lived, non-dividing cells like neurons are linked to neurodegenerative diseases like Alzheimer's. A study now finds that the build-up of these ...

Tsukuba, Japan—In many mammals, a limited number of oocytes are responsible for producing the next generation. Oocytes grow within follicles, which consist of an oocyte and the surrounding granulosa ...