Patients with serum ferritin levels higher than 1000 μg/L show a 91% increased risk for any fracture, with a doubled risk for vertebral and humerus fractures compared with those without iron overload.

BERLIN—Kidney transplant recipients who have iron overload are at increased risk for bacterial infection compared with those who have normal iron levels, according to preliminary results of a Spanish ...

A case report highlights pulmonary siderosis in a welder with progressive dyspnea and recurrent infections, underscoring occupational history, possible systemic iron overload, and the need to monitor ...

Merganser Biotech, a drug licensing and development startup, has secured funding from a consortium that includes BioAdvance, the Biotechnology Greenhouse of Southeastern Pennsylvania and individual ...

Iron overload is prevalent among adults with sickle cell disease (SCD), according to a study presented at the annual meeting of the American Society of Hematology, held from Dec. 6 to 9 in Orlando, ...

BMP, bone morphogenetic protein; BMPR, bone morphogenetic protein receptor; HAMP, hepcidin; HFE, hereditary hemochromatosis protein; HJV, hemojuvelin; Holo-Tf, holo ...

Expert Rev Mol Diagn. 2010;10(6):755-763. The diagnosis is based on a three-step strategy. The first step is recognizing clinical signs and symptoms. Many symptoms in various combinations may suggest ...

The clinical introduction of hepcidin25 (Hep25) has led to a more detailed understanding of its relationship with ferroportin (FP) and divalent metal transporter1 in primary iron overload syndromes ...

Iron overload is prevalent among adults with sickle cell disease (SCD), according to a study presented at the annual meeting of the American Society of Hematology, held from Dec. 6 to 9 in Orlando, ...

Saturation of TfR1 leads to the dissociation of Hfe and the binding of the alter to the TfR2, which in turn influences the binding of BMP6 to its receptors on the membrane. Increased liver iron ...