These intercellular messages, ferried about by molecules called interferons, serve as a warning signal to nearby cells—“‘You are about to be infected; it’s time for you to set up an antiviral state,’” ...

When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

Bonn, November 8, 2022 - The innate immune system fights infectious agents. The alarm messenger interferon plays a central role in this. However, if it is produced in the absence of an infection, it ...

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.

Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain. The resulting ...

Researchers have discovered that Type I interferon (IFN) plays a key role in helping the immune system effectively target viruses, while stopping white blood cells from 'going rogue' and attacking the ...

A new study shows that about two percent of the population develop autoantibodies against type 1 interferons, mostly later in life. This makes individuals more susceptible to viral diseases like COVID ...

A common cold can feel like a small thing until it is not. One day you feel fine, and the next you wake up congested, drained ...

In 2020, Ashley Harms, Ph.D., and University of Alabama at Birmingham colleagues published an Acta Neuropathologica study that used a mouse model to show that the alpha-synuclein pathology from ...