The past decade has delivered landmark advances in human and medical genomics that shape how we understand disease mechanisms ...
From data to deployment. Pipeline from single-base tokenization of >600 high-quality human ge-nomes into a MoE Transformer optimized for up to ~1 Mb context, and downstream use for embed-dings, ...
An international team of scientists has decoded some of the most stubborn, overlooked regions of the human genome using complete sequences from 65 individuals across diverse ancestries. This milestone ...
Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and ...
The Indigenous peoples of the Bolivian highlands are survivors. For thousands of years they have lived at altitudes of more than two miles, where oxygen is about 35 percent lower than at sea level.
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Replacing large mouse gene regions with human DNA
Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes with entire human sequences has posed significant technical challenges. The ...
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