There is no cure for the rare disease Hereditary Spastic Paraplegia (HSP), but researchers from Drexel University’s College of Medicine and the UMass Chan Medical School have achieved ...

Hereditary Spastic Paraplegia (HSP) encompasses a heterogeneous group of genetic neurodegenerative disorders primarily characterised by progressive lower-limb spasticity and weakness. The condition ...

A disease-causing gene in hereditary spastic paraplegia bolsters the theory of altered lipid processing as a shared cause in motor neuron diseases. Genetic and cellular studies, led by Andrew Crosby ...

NASHVILLE, Tenn. (WKRN) – Imagine losing the strength in the muscles of your legs and not knowing why. The condition is often misdiagnosed and worsens with time. It’s a rare reality for about 20,000 ...

In a recent publication in Molecular Therapy, researchers from Drexel University College of Medicine and UMass Chan Medical School presented a silence-and-replace gene therapy strategy aiming to ...

There is no cure for the rare disease Hereditary Spastic Paraplegia (HSP), but researchers from Drexel University's College of Medicine and the UMass Chan Medical School have achieved ...

Boston Children’s Hospital has received $8.1M in NIH funding to support and expand the Spastic Paraplegia Centers of Excellence Research Network (SP-CERN). Darius Ebrahimi-Fakhari, M.D., Ph.D., ...

Researchers from the University of Seville and the Seville Institute of Biomedicine (IBiS), in collaboration with the University of Cambridge, have identified a new role for one of the genes related ...

Boston Children's Hospital has received $8.1M in NIH funding to support and expand the Spastic Paraplegia Centers of Excellence Research Network (SP-CERN). Darius Ebrahimi-Fakhari, M.D., Ph.D., ...