Glycogen storage diseases (GSDs) constitute a group of inherited metabolic disorders that impair normal glycogen synthesis or degradation, resulting in the accumulation of structurally abnormal ...

McArdle disease, also known as glycogen storage disease type V, is an inherited metabolic disorder marked by a deficiency of myophosphorylase, the enzyme essential for the breakdown of glycogen in ...

Glycogen storage disorders are metabolic conditions that manifest in the first years of life. This inability to process and store glucose can be difficult to diagnose. Now, researchers who have ...

Glycogen storage disease (GSD) refers to a group of rare genetic conditions that affect how the body stores and breaks down glycogen. The most common type is type I, also called von Gierke disease.

Boston, MA - A syndrome that included exercise intolerance and a kind of hypertrophic cardiomyopathy was identified in several children in a family of Syrian descent, many of whom were ultimately ...

A potential treatment strategy for an often-fatal inherited glycogen storage disease has been identified by researchers. Patients with the disorder lack the enzyme that enables their livers to convert ...

COLUMBIA, Mo. - Glycogen storage disorders, which affect the body's ability to process sugar and store energy, are rare metabolic conditions that frequently manifest in the first years of life. Often ...

Researchers from Maze Therapeutics Inc. presented the discovery and preclinical characterization of a novel selective small-molecule inhibitor of glycogen synthase 1 (GYS1), MZ-101, as a potential ...