When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.

Scientists at St. Jude Children’s Research Hospital discovered that metabolism controls regulatory T cells, the “brakes” of the immune system (MEMPHIS, Tenn. – October 24, 2025) Metabolism guides the ...

Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

Mitochondria isolated from onions entered lung immune cells in mice and restored their energy balance, revealing an unexpected way plant-derived organelles can regulate inflammation inside mammalian ...

Both autoimmune and autoinflammatory diseases (AIDs) are characterised by bouts of hyperactivation of immune reactions ...