A new genetic and clinical analysis suggests that atypical depression represents a distinct biological subtype of the ...

In a recent study published in JAMA Network Open, researchers explored how structural and functional aspects of the brain, as seen through neuroimaging, differ between individuals with high exposure ...

Neuroscientists have long relied on functional magnetic resonance imaging (fMRI) to identify patterns of activity in the brain by measuring changes in blood flow. This has been an invaluable tool for ...

Patients are commonly diagnosed with treatment-resistant depression when they do not improve despite receiving two or more pharmacologic treatments for an adequate dose and duration during the same ...

Treatment-resistant (refractory) depression has been a fertile topic for several decades (e.g., Freyhan, 1978; Nierenberg & Amsterdam, 1990; Voineskos, 2020). Unfortunately, as noted by Voineskos, ...