Scientists look at the base pairs that compose the "rungs" of the DNA ladder to determine a genome's sequence. The success of E. coli bacteria depends on their ability to multiply very rapidly by ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

DNA is the raw material of modern medicine yet is the only part of drug development not accessible at the lab bench. DNA synthesis, the first step in most biological workflows including gene synthesis ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

DNA synthesis is vital to several processes in biopharmaceutical innovation, including the development of gene therapies, CRISPR gene editing, antisense oligonucleotides and RNA therapies. The need ...

Illinois biochemistry professor Satish Nair and his colleagues discovered a new class of DNA-protein hybrids and determined the mechanisms by which they are formed in bacterial cells. The findings ...

Every researcher knows the frustration: your groundbreaking experiment is on hold because the DNA sequence you need is "unmanufacturable". Or worse, after weeks of waiting, the oligos arrive with ...