Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...

Toward the goal of efficient editing of farm animals for genetic improvements, this study explores an upgraded form of nuclease PE (uPEn). Based on the resolved structure of the NiV polymerase L-P ...

Prof. Liu Cong from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, along with collaborators, ...

The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases. To better understand how chromatin ...

Cryo-electron microscopy (cryo-EM) has revolutionalized our understanding of the intricate molecular machinery that governs life. It has elucidated the three-dimensional (3D) structure of biological ...

HIV is a lifelong infection that, without proper antiviral treatment, will kill cells of the immune system and leave individuals susceptible to infections and cancers. The longevity of this virus ...