Centromeres are curious structures. These specially organized chromosomal regions are best known for their unique and critical role in cell division, in which they are well understood to serve as the ...

Researchers from the Kops group in collaboration with researchers from the University of Edinburgh, made a surprising new discovery in the structure of the centromere, a structure that is involved in ...

Despite the immense amount of genetic material present in each cell, around three billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities.

Super-resolution microscopy image of a mitotic chromosome (white) with the centromeres of each sister chromatid depicted in orange. Each centromere consists of two distinct chromatin subdomains ...

Cell division is an essential process by which living organisms grow, replenish lost cells, and regenerate dead and damaged tissues. When a parent cell divides into two daughter cells, ...

Researchers propose a two-step regulatory mechanism for non-Rabl configurations of centromeres in the nucleus. Centromeres are chromosomal domains that link pairs of sister chromatids together during ...

A genomic study of human and selected nonhuman primate centromeres has revealed their unimaginable diversity and speed of evolutionary change. Although centromeres are vital to proper cell replication ...

Two different types of centromeres evolved from a monocentromere, a macro-monocentromere in Cha. luteum and a holocentromere in Chi. japonica. Micrographs show mitotic chromosomes. The centromere is ...

Left: Arabidopsis thaliana with healthy centromere division. Right: A mutant version of Arabidopsis with uneven centromere division. Credit: Cold Spring Harbor Laboratory Left: Arabidopsis thaliana ...