CSF-ctDNA was detected in 59% of cases and showed high concordance (84%) with tumor mutations. Lower variant allelic frequency in CSF-ctDNA was associated with significantly worse survival outcomes.
Cerebrospinal fluid (CSF) leaks may be one of the mechanisms that link traumatic brain injury (TBI) with dementia, according to a recently published hypothesis in Alzheimer's & Dementia: Translational ...