Amidation reactions are the most common reactions in the chemical industry. They are indispensable for a wide range of industrial production processes, but their ecological footprint is highly ...

The carbon-hydrogen bonds in alkanes -- particularly those at the ends of the molecules, where each carbon has three hydrogen atoms bound to it -- are very hard to 'crack' if you want to replace the ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Figure 1: Selective amidation reaction using newly designed iridium (Ir) catalysts. Abundant in nature Hydrocarbons are used as substrates to synthesize nitrogen-containing ring, called gamma-lactams.

This presentation will provide a comprehensive overview of the synthetic strategy and process development for the key secondary amide intermediate in the synthesis of bersacapavir. First, two ...