Recently these monocyte-derived alveolar macrophages, or Mo-AMs, were identified as key drivers of lung fibrosis disease progression. However, the mechanisms of their pro-fibrotic behavior and ...

Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal conditions, these cells act as guardians, keeping the lungs healthy, supporting breathing, and ...

Researchers have discovered that lung-based immune cells can be "trained" to remember a previously encountered pathogen, making them more efficient at clearing out the cellular debris that accumulates ...

Playing tag, riding bikes, and climbing trees are among the many joys of childhood that leave kids happily worn out and panting heavily for air. For those with lung disorders, growing up can look ...

Scientists discovered a novel self-perpetuating cancer mechanism in the lung microenvironment, wherein EGFR-driven lung adenocarcinoma cells exploit lung-resident macrophages -- remodeling them to ...