In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A gene in schizophrenia.

Schizophrenia is a complex mental health disorder, but scientists are learning more about what can cause it... | Genetics And ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

In 2023, Krainer published a paper in which he showed SRSF1’s involvement in PDAC. The most common form of pancreatic cancer, PDAC is also the most life- threatening. By increasing SRSF1 into a system ...

Computational biologists from the National University of Singapore (NUS) have uncovered how RNA splicing—a crucial process for isoform expression and protein diversity—is regulated across different ...

The immune system's gradual decline with age, known as immune aging, increases susceptibility to infections, autoimmune diseases, and cancers. T cells, crucial for adaptive immunity, undergo ...

Cold Spring Harbor Laboratory researchers have reported that a bespoke antisense oligonucleotide can disrupt alternative ...

In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative splicing, which may allow a lowly ...

New research suggests that alternative splicing may have an even greater influence on biology than just by creating new protein isoforms. The study shows that the biggest impact of alternative ...

Study design to create a database of transcripts, called TRAILS (TRAnscriptomic resource of Immune cells using Long-read Sequencing), from different human immune cell subsets and downstream analysis.