AMX0114 is an investigational antisense oligonucleotide targeting calpain-2, a calcium-activated protease believed to play a role in ALS disease progression. The Food and Drug Administration (FDA) has ...

Add Yahoo as a preferred source to see more of our stories on Google. Eric Dane is opening up and being completely vulnerable with fans in his first video addressing his ALS diagnosis and a new ...

Eric Dane advocated for a cure for Amyotrophic Lateral Sclerosis (ALS) as the progression of his symptoms was on full display in a campaign video. After the “Euphoria” actor missed the planned “Grey’s ...

Please provide your email address to receive an email when new articles are posted on . AMX0114 was developed to target calpain-2, a driver of axonal neurodegeneration. A pending clinical trial will ...

Darin Nakakihara doesn’t remember much from the day that changed his life. He left the doctor’s office and walked to his car. In the driver’s seat, he looked up the disease he was just diagnosed with, ...

- AMX0114 is an Amylyx-developed antisense oligonucleotide designed to target calpain-2, a key contributor to the axonal degeneration pathway in ALS - Phase 1 LUMINA trial of AMX0114 underway; early ...

A recent large study conducted in Sweden has found that long-term exposure to elevated levels of air pollution may increase the risk for the development of motor neuron disease (MND), as well as ...

The first platform trial for amyotrophic lateral sclerosis (ALS), which individually evaluated four experimental drugs, failed to meet key primary endpoints. Still, investigators view the trial as ...