IDSA recommends shorter antibiotic courses for adults with cUTIs who show clinical improvement on effective therapy.

Background and aims: Urinary tract infections (UTIs) are relatively common infections in children. Findings on nuclear renal scans suggest that the vast majority of infants and young children with ...

Tebipenem pivoxil hydrobromide is an orally bioavailable carbapenem with activity against uropathogenic Enterobacterales. Oral tebipenem pivoxil hydrobromide (HBr), a carbapenem, is as effective as ...

Cefepime-taniborbactam, an investigational beta-lactam and beta-lactamase inhibitor combination, was superior to meropenem for the treatment of hospitalized patients with complicated urinary tract ...

"The five factors with the highest odds of developing APN included obstructive and reflux uropathy, presentation to an acute care facility, urinary retention, history of UTI, and renal comorbidities.

A young male cadaveric kidney transplant developed delayed graft function. In addition to fever, serial allograft biopsies revealed progressive infiltration of polymorphonuclear leukocytes. After ...

Exblifep is a combination product that consists of cefepime, a cephalosporin antibacterial, and enmetazobactam, a beta-lactamase inhibitor. The Food and Drug Administration (FDA) has approved Exblifep ...

Wockhardt announced that its novel intravenous antibiotic Foviscu (WCK 4282) has successfully met the primary endpoint in a Phase 3 clinical trial in patients with complicated urinary tract infections ...

Credit: Getty Images. The application includes data from the phase 3 ADAPT-PO trial, which evaluated the efficacy and safety of tebipenem HBr in 868 adults with cUTI or acute pyelonephritis. The Food ...

GlaxoSmithKline (GSK) has resubmitted a new drug application (NDA) to the US Food and Drug Administration seeking approval of tebipenem pivoxil hydrobromide (HBr), an investigational oral carbapenem ...